Presentation:
A sterile aqueous solution containing:
Oxytetracycline Dihydrate equivalent to 200mg/ml of oxytetracycline base.
Sodium Formaldehyde Sulphoxylate Dihydrate (0.4%w/v).
Uses:
Alamycin LA is specifically formulated to provide a prolonged action resulting in sustained antibacterial activity. Blood levels persist for at least 4 days. After administration by the intramuscular route maximum blood levels are achieved after 4 to 8 hours making Alamycin LA suitable for the treatment of acute infections.
Oxytetracycline has been shown to be effective in vitro against the following bacterial species:Bordetella bronchiseptica, Arcanobacterium pyogenes, Erysipelothrix rhusiopathiae, Escherichia coli, Haemophilus somnus, Mannheimia haemolytica, Pasteurella multocida, Salmonella dublin, Staphylococcus aureus, Streptococcus agalactiae, Streptococcus faecalis, Streptococcus pyogenes and Streptococcus uberis.
Alamycin LA is indicated for use in cattle, sheep and pigs in the treatment of: atrophic rhinitis caused by Bordetella bronchiseptica, Mannheimia haemolytica and Pasteurella multocida; navel/joint ill caused by Arcanobacterium pyogenes, E. coli, and Staphylococcus aureus; mastitis caused by Arcanobacterium pyogenes, E. coli, Staphylococcus aureus, Streptococcus agalactiae, and Streptococcus uberis;metritis caused by E. coli and Streptococcus pyogenes; pasteurellosis and infections of the respiratory tract caused by Mannheimia haemolytica and Pasteurella multocida; septicaemia caused by Salmonella dublin and Streptococcus pyogenes; erysipelas caused by Erysipelothrix rhusiopathiae.
Alamycin LA can also be used in the control of enzootic abortion in sheep.
Dosage & Administration:
The recommended dosage rate is 20mg/kg bodyweight (1ml per 10kg bodyweight) by deep intramuscular injection. The product is recommended for a single administration only.
Withdrawal Period:
Milk for human consumption: Milk taken from cows should not be used for human consumption during treatment or for 10 days after treatment. Sheep’s milk may not be used for human consumption during treatment or for 7 days after treatment.
Meat for human consumption: Cattle, Sheep and Pigs must not be slaughtered for human consumption during treatment. Cattle may be slaughtered for human consumption only after 31 days from last treatment and Sheep only after 9 days from last treatment. Pigs may be slaughtered for human consumption after a period of 18 days following last treatment.
Contraindictions, Warnings etc:
When the container is broached for the first time, the date on which any product remaining in the container should be discarded should be calculated and recorded.
A statement of the in-use shelf life of the product is given on the package insert. This discard date should be written in the space provided on the primary label.
Do not dilute Alamycin LA. Although Alamycin LA is well tolerated, occasionally a slight reaction of a transient nature has been observed. The use of tetracyclines during the period of tooth and bone development, including late pregnancy, may lead to discolouration. If concurrent treatment is administered, use a separate injection site. Wash hands after use. In case of contact with eyes or skin, wash immediately with water as irritation may occur. Take care to avoid accidental injection.
Pharmaceutical Precautions:
Do not store above 25ºC. Protect from light. Following withdrawal of the first dose, use the product within 28 days. Discard unused material. Keep container in outer carton. Dispose of any unused product and empty containers in accordance with guidance from your local waste regulation authority.
Further Information:
If stored as directed Alamycin LA can be expected to retain its potency for 2 years from the manufacturing date.
When the vial has been broached and the contents exposed to air, the solution may darken but the potency will be unchanged.